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GeneCards Summary for ADA Gene. ADA (Adenosine Deaminase) is a Protein Coding gene. Diseases associated with ADA include Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Negative, Due To Adenosine Deaminase Deficiency and Severe Combined Immunodeficiency Due To Adenosine Deaminase Deficiency . what does joker mean in cards